PFI-3
(CAS No:1819363-80-8)
QC Documents
ChemicalInfomation
CAS No: |
1819363-80-8 |
Molecular formula(MF) |
C19H19N3O2 |
Molecular Weight(MW): |
321.37 |
Alias |
|
Solubility
In vitro |
DMSO
|
64 mg/mL
(199.14 mM)
|
Water
|
<1 mg/mL
|
Ethanol
|
<1 mg/mL
|
In vivo |
|
|
Biological Activity
Description |
PFI-3 is a selective chemical probe for SMARCA bromodomains, including SMARCA2, SMARCA4 and PB1(5) bromodomains.
|
Targets
|
SMARCA2 [1] |
SMARCA4 [1] |
PB1(5) bromodomains [1] |
|
In vitro |
PFI-3 shows a significant selectivity for PB1(5) and SMARCA2/4 over 36 other tested kinases. [1]
|