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Bikinin

(CAS No:188011-69-0)
Bikinin is an ATP-competitive Arabidopsis GSK-3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling.
CAS No:188011-69-0
Molecular Weight(MW):273.08
Purity:99.00%
Specification:500MG;1G;5G;10G;50G;100G
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QC Documents
 COA  MSDS  HPLC  NMR
ChemicalInfomation
CAS No: 188011-69-0
Molecular formula(MF) C9H9BrN2O3
Molecular Weight(MW): 273.08
Alias
Solubility
In vitro DMSO 54 mg/mL (197.74 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
In vivo
Biological Activity
Description Bikinin is an ATP-competitive Arabidopsis GSK-3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling.
Targets
GSK-3 [1]
In vitro

Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. [1] Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line. [3]

In vivo Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo. [2]