Optovin
(CAS No:348575-88-2)
QC Documents
ChemicalInfomation
CAS No: |
348575-88-2 |
Molecular formula(MF) |
C15H13N3Os2 |
Molecular Weight(MW): |
315.41 |
Alias |
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Solubility
In vitro |
DMSO
|
63 mg/mL
warmed
(199.74 mM)
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Water
|
<1 mg/mL
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Ethanol
|
<1 mg/mL
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In vivo |
|
|
Biological Activity
Description |
Optovin is a reversible photoactivated TRPA1 activator.
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Targets
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In vitro |
Optovin activates human TRPA1 via structure dependent photochemical reactions. [1]
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In vivo |
Optovin enables real-time optical control of neurons, and also elicits nociceptive behaviors in adult mice. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. [1]
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