N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine
(CAS No:55778-02-4)
QC Documents
ChemicalInfomation
CAS No: |
55778-02-4 |
Molecular formula(MF) |
C18H18N4 |
Molecular Weight(MW): |
290.36 |
Alias |
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Solubility
In vitro |
DMSO
|
30 mg/mL
(103.32 mM)
|
Water
|
<1 mg/mL
|
Ethanol
|
<1 mg/mL
|
Biological Activity
Description |
WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM. |
Targets
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In vitro |
WZ811 is a highly potent competitive antagonist of CXCR4. WZ811 is effective in counteracting SDF-1 on cAMP reduction at doses as low as a few nanomoles. WZ811 blocks SDF-1-mediated invasion with EC50 of 5.2 nM. [1]
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