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GSK1278863

(CAS No:960539-70-2)
Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. Phase 2.
CAS No:960539-70-2
Molecular Weight(MW):393.43
Purity:99.00%
Specification:500MG;1G;5G;10G;50G;100G
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QC Documents
 COA  MSDS  HPLC  NMR
ChemicalInfomation
CAS No: 960539-70-2
Molecular formula(MF) C19H27N3O6
Molecular Weight(MW): 393.43
Alias
Solubility
In vitro DMSO 10 mg/mL warmed (25.41 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
In vivo
Biological Activity
Description Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. Phase 2.
Targets
HIF-PH [1]
In vitro

GSK1278863 induces an effective EPO response and stimulates non-EPO mechanisms for erythropoiesis. [1]